I'm the guy on the Internet who doesn't reflexively hate Seth MacFarlane. His shows can be hit-or-miss, but he's ridiculously talented in his own right and when he's "on" he and his 'family' of writers/actors routinely pull off some great stuff. In any case, he's now branched out into feature films; and his debut feature - shocker! - centers around a lovable jerk whose best buddy is a thing-that-should-not-talk-or-act-like-a-human-and-yet-does voiced by MacFarlane himself:
The "big idea" is that it's the hypothetical sequel to every "boy and his magical friend" story ever: Mark Wahlberg's character wished his Teddy Bear to life as a child, but now it's two decades later and his "magical adventure pal" is now his "magical perpetually-adolescent-troublemaker-who-gets-in-the-way-of-his-relationships pal."
I think it looks hysterical. I love that Ted's design is just "basic bear," and MacFarlane-alumni Kunis is always fun in these things.